Where did the super-small sized large bowel advanced cancer come from?

Ryo Wada1, Koichi Sato2, Takafumi Ichida3, Hiroshi Maekawa2, Kaoru Ogawa3, Takeo Maekawa2
1Department of Pathology, Juntendo Shizuoka Hospital of Juntendo University School of Medicine, Shizuoka, Japan
2Department of Surgery, Juntendo Shizuoka Hospital of Juntendo University School of Medicine, Shizuoka, Japan
3Department of Gastroenterology, Juntendo Shizuoka Hospital of Juntendo University School of Medicine, Shizuoka, Japan
DOI: 10.1186/1477-3163-6-7

ABSTRACT

Although most of the large bowel advanced cancers (the carcinoma invaded into the muscularis propria or deeper zone by Japanese criteria [1]), or T2 and T3 by UICC classification [2]) are 3 – 6 cm in maximum (max.) diameter, those less than 2 cm in max. diameter were sometimes found, today. However, nobody knows what is the pre-lesion of these small sized large bowel advanced cancer.

In the current study, using the characteristics of the histological features of the large bowel cancers with invasion to the submucosal layer (SM-C), the histogenesis of the super-small sized large bowel advanced cancers less than 15 mm in max. diameter (SS-AC) were analyzed pathologically, and some findings were revealed for clearing the question described above.