Table 1

Allele frequencies of SNPs in the BRAF gene in the German cohort. Location of SNPs within BRAF and refSNP Ids are listed.
SNP Id.
 dbSNP rs#
 Exon/Intron*
 M case
 M control
 p-value
 F case
 F control
 p-value
BRAF-1
 rs1639679
 Intron 11
 C = 0.888
 C = 0.927
 0.045
 C = 0.943
 C = 0.934
 0.585



A = 0.112
 A = 0.073
A = 0.057
 A = 0.066
BRAF-2
 rs1267646
 Intron 9
 C = 0.839
 C = 0.870
 0.240
 C = 0.870
 C = 0.867
 0.914



T = 0.161
 T = 0.130
T = 0.130
 T = 0.133
BRAF-3
 rs1267606
 Intron 2
 T = 0.890
 T = 0.925
 0.078
 T = 0.942
 T = 0.930
 0.477



G = 0.110
 G = 0.075
G = 0.057
 G = 0.070
BRAF-4
 rs1267621
 Intron 1
 G = 0.839
 G = 0.873
 0.147
 G = 0.868
 G = 0.880
 0.584



A = 0.171
 A = 0.127
A = 0.132
 A = 0.120
BRAF-5
 rs1267601
 Intron 2
 A = 0.894
 A = 0.932
 0.041
 A = 0.944
 A = 0.935
 0.526



G = 0.106
 G = 0.068
G = 0.056
 G = 0.065
BRAF-6
 rs1267609
 Intron 3
 C = 0.882
 C = 0.907
 0.008
 C = 0.945
 C = 0.935
 0.539



T = 0.118
 T = 0.093
T = 0.055
 T = 0.065
BRAF-7
 rs1267636
 Intron 8
 A = 0.891
 A = 0.939
 0.010
 A = 0.945
 A = 0.935
 0.517



G = 0.109
 G = 0.061
G = 0.055
 G = 0.065
BRAF-8
 rs1267649
 Intron 5
 G = 0.896
 G = 0.934
 0.038
 G = 0.945
 G = 0.934
 0.474



C = 0.104
 C = 0.066
C = 0.055
 C = 0.066
BRAF-9
 rs1639675
 Intron 7
 A = 0.891
 A = 0.930
 0.041
 A = 0.945
 A = 0.939
 0.719



G = 0.109
 G = 0.070
G = 0.055
 G = 0.061
BRAF-10
 rs1267610
 Intron 3
 G = 0.732
 G = 0.770
 0.187
 G = 0.766
 G = 0.784
 0.507



A = 0.268
 A = 0.230
A = 0.234
 A = 0.216
BRAF-11
 rs1267625
 Intron 2
 T = 0.833
 T = 0.870
 0.135
 T = 0.872
 T = 0.864
 0.716



G = 0.167
 G = 0.130
G = 0.128
 G = 0.136
BRAF-12
 rs1267618
 Intron 1
 G = 0.837
 G = 0.871
 0.146
 G = 0.868
 G = 0.867
 0.961



A = 0.163
 A = 0.129
A = 0.132
 A = 0.133

* within the 18 exon transcript ENST00000288602

Meyer et al. Journal of Carcinogenesis 2003 2:7   doi:10.1186/1477-3163-2-7