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  Indian J Med Microbiol
 

Figure 5: Histopathology of representative tumors from TP53−/−and TP53+/− hamsters. Neoplastic lymphocytes (lymphoma) infiltrate among skeletal muscle fibers (a), peri-epididymal collagen fibers (b), and cardiac myocytes (f), and expand the splenic red pulp (g) and the renal interstitium (i). Neoplastic lymphocytes within a pulmonary blood vessel (leukemia; c). Neoplastic endothelial cells (hemangiosarcoma) form vascular channels within the liver (d) and dermis (h). Neoplastic squamous epithelial cells (squamous cell carcinoma) form an expansive mass within the dermis (e). (a-i) Hematoxylin and eosin stains. Scale bars: 150 μm

Figure 5: Histopathology of representative tumors from <i>TP53<sup>−/−</sup></i>and <i>TP53<sup>+/−</sup></i> hamsters. Neoplastic lymphocytes (lymphoma) infiltrate among skeletal muscle fibers (a), peri-epididymal collagen fibers (b), and cardiac myocytes (f), and expand the splenic red pulp (g) and the renal interstitium (i). Neoplastic lymphocytes within a pulmonary blood vessel (leukemia; c). Neoplastic endothelial cells (hemangiosarcoma) form vascular channels within the liver (d) and dermis (h). Neoplastic squamous epithelial cells (squamous cell carcinoma) form an expansive mass within the dermis (e). (a-i) Hematoxylin and eosin stains. Scale bars: 150 μm