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  Indian J Med Microbiol
 

Figure 3: An illustration of a possible SATB2 and Runt-related transcription factor 2 network in carcinogenesis. SATB2 and Runt-related transcription factor 2 are linked by multiple microRNAs in the pathways of carcinogenesis. Improper activation of Runt-related transcription factor 2 might also be induced by SATB2 via β-catenin/NF-κB pathway under a prolonged inflammation condition. Runt-related transcription factor 2 and SATB2 also share many downstream targets such as B-cell lymphoma 2, c-MYC, and vascular endothelial growth factor in mediating cell transformation

Figure 3: An illustration of a possible SATB2 and Runt-related transcription factor 2 network in carcinogenesis. SATB2 and Runt-related transcription factor 2 are linked by multiple microRNAs in the pathways of carcinogenesis. Improper activation of Runt-related transcription factor 2 might also be induced by SATB2 via β-catenin/NF-κB pathway under a prolonged inflammation condition. Runt-related transcription factor 2 and SATB2 also share many downstream targets such as B-cell lymphoma 2, c-MYC, and vascular endothelial growth factor in mediating cell transformation